CBLC

GENE INFORMATION

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Gene name

CBLC (HGNC Symbol)

Synonyms

CBL-3, CBL-SL, RNF57

Description

Cbl proto-oncogene C, E3 ubiquitin protein ligase (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

Chromosome

19

Cytoband

q13.32

Chromosome location (bp)

44777869 - 44800634

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000142273 (version 78.38)

Entrez gene

23624

UniProt

Q9ULV8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9ULV8

Antibodypedia

CBLC antibodies
 

PROTEIN VIEW

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CBLC-001
 
CBLC-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CBLC-001 ENSP00000270279
ENST00000270279
Q9ULV8
Show all »
Show » Show » 474 52.5 No 0
CBLC-002 ENSP00000340250
ENST00000341505
Q9ULV8
Show all »
Show » Show » 428 47.4 No 0