SH3GL1

GENE INFORMATION

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Gene name

SH3GL1 (HGNC Symbol)

Synonyms

CNSA1, EEN, MGC111371, SH3D2B, SH3P8

Description

SH3-domain GRB2-like 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

4360370 - 4400547

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000141985 (version 78.38)

Entrez gene

6455

UniProt

Q99961 (UniProt - Evidence at protein level)

neXtProt

NX_Q99961

Antibodypedia

SH3GL1 antibodies
 

PROTEIN VIEW

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SH3GL1-001
 
SH3GL1-002
 
SH3GL1-003
 
SH3GL1-004
 
SH3GL1-005
 
SH3GL1-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SH3GL1-001 ENSP00000269886
ENST00000269886
Q99961
Show all »
Show » Show » 368 41.5 No 0
SH3GL1-002 ENSP00000404568
ENST00000417295
Q99961
Show all »
Show » Show » 320 36.3 No 0
SH3GL1-003 ENSP00000470792
ENST00000598564
Q99961
Show all »
Show » Show » 304 34.5 No 0
SH3GL1-004 ENSP00000471260
ENST00000593591
M0R0I3
Show all »
Show » Show » 139 15.8 No 0
SH3GL1-005 ENSP00000472640
ENST00000598219
M0R2K6
Show all »
Show » 27 3.1 No 0
SH3GL1-006 ENSP00000469766
ENST00000598230
M0QYE0
Show all »
Show » Show » 129 14.4 No 0