RPTOR

GENE INFORMATION

? »

Gene name

RPTOR (HGNC Symbol)

Synonyms

KIAA1303, KOG1, Mip1, raptor

Description

Regulatory associated protein of MTOR, complex 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Chromosome

17

Cytoband

q25.3

Chromosome location (bp)

80544819 - 80966371

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000141564 (version 78.38)

Entrez gene

57521

UniProt

Q8N122 (UniProt - Evidence at protein level)

neXtProt

NX_Q8N122

Antibodypedia

RPTOR antibodies
 

PROTEIN VIEW

? »
 
 
 
RPTOR-001
 
RPTOR-005
 
RPTOR-006
 
RPTOR-011
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RPTOR-001 ENSP00000307272
ENST00000306801
Q8N122
Show all »
Show » Show » 1335 149 No 1
RPTOR-005 ENSP00000460136
ENST00000570891
Q8N122
Show all »
Show » Show » 379 43.3 No 0
RPTOR-006 ENSP00000442479
ENST00000544334
Q8N122
Show all »
Show » Show » 1177 131.5 No 1
RPTOR-011 ENSP00000460940
ENST00000576366
I3L436
Show all »
Show » 235 24.7 No 0