ADCYAP1

GENERAL INFORMATION

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Gene name

ADCYAP1

Gene description

Adenylate cyclase activating polypeptide 1 (pituitary)

Protein class

Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (appendix, gallbladder)
GTEx:Tissue enhanced (cerebral cortex)

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (appendix, gallbladder)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cerebral cortex)

Organ

Expression



GENE INFORMATION

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Gene name

ADCYAP1 (HGNC Symbol)

Synonyms

PACAP

Description

Adenylate cyclase activating polypeptide 1 (pituitary) (HGNC Symbol)

Entrez gene summary

This gene encodes a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]

Chromosome

18

Cytoband

p11.32

Chromosome location (bp)

904943 - 912172

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000141433 (version 78.38)

Entrez gene

116

UniProt

P18509 (UniProt - Evidence at protein level)

neXtProt

NX_P18509

Antibodypedia

ADCYAP1 antibodies


PROTEIN BROWSER

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ENST00000450565
 
ENST00000579794
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADCYAP1-002 ENSP00000411658
ENST00000450565
P18509
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Show » Show » 176 18.8 Yes 0
ADCYAP1-003 ENSP00000462647
ENST00000579794
P18509
Show all »
Show » Show » 176 18.8 Yes 0