SKAP1

GENE INFORMATION

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Gene name

SKAP1 (HGNC Symbol)

Synonyms

SCAP1, SKAP55

Description

Src kinase associated phosphoprotein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q21.32

Chromosome location (bp)

48133440 - 48430275

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000141293 (version 78.38)

Entrez gene

8631

UniProt

Q86WV1 (UniProt - Evidence at protein level)

neXtProt

NX_Q86WV1

Antibodypedia

SKAP1 antibodies
 

PROTEIN VIEW

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SKAP1-001
 
SKAP1-002
 
SKAP1-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SKAP1-001 ENSP00000338171
ENST00000336915
Q86WV1
Show all »
Show » Show » 359 41.4 No 0
SKAP1-002 ENSP00000464311
ENST00000584924
Q86WV1
Show all »
Show » Show » 359 41.4 No 0
SKAP1-005 ENSP00000464198
ENST00000579336
J3QRG3
Show all »
Show » 99 11.3 No 0