OSGIN1

GENE INFORMATION

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Gene name

OSGIN1 (HGNC Symbol)

Synonyms

BDGI, OKL38

Description

Oxidative stress induced growth inhibitor 1 (HGNC Symbol)

Entrez gene summary

This gene encodes an oxidative stress response protein that regulates cell death. Expression of the gene is regulated by p53 and is induced by DNA damage. The protein regulates apoptosis by inducing cytochrome c release from mitochondria. It also appears to be a key regulator of both inflammatory and anti-inflammatory molecules. The loss of this protein correlates with uncontrolled cell growth and tumor formation. Naturally occurring read-through transcription exists between this gene and the neighboring upstream malonyl-CoA decarboxylase (MLYCD) gene, but the read-through transcripts are unlikely to produce a protein product. [provided by RefSeq, Aug 2011]

Chromosome

16

Cytoband

q23.3

Chromosome location (bp)

83948282 - 83966332

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000140961 (version 78.38)

Entrez gene

29948

UniProt

Q9UJX0 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9UJX0

Antibodypedia

OSGIN1 antibodies
 

PROTEIN VIEW

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OSGIN1-001
 
OSGIN1-002
 
OSGIN1-003
 
OSGIN1-006
 
OSGIN1-007
 
OSGIN1-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

OSGIN1-001 ENSP00000343376
ENST00000343939
Q9UJX0
Show all »
Show » Show » 560 60.8 No 0
OSGIN1-002 ENSP00000376983
ENST00000393306
Q9UJX0
Show all »
Show » Show » 477 52 No 0
OSGIN1-003 ENSP00000355374
ENST00000361711
Q9UJX0
Show all »
Show » Show » 477 52 No 0
OSGIN1-006 ENSP00000462048
ENST00000565123
J3KRK7
Show all »
Show » Show » 163 17.9 No 0
OSGIN1-007 ENSP00000456965
ENST00000561552
H3BT09
Show all »
Show » 105 11.4 No 0
OSGIN1-008 ENSP00000457157
ENST00000567707
H3BTF9
Show all »
Show » Show » 123 13.3 No 0