CRTC3

GENE INFORMATION

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Gene name

CRTC3 (HGNC Symbol)

Synonyms

FLJ21868

Description

CREB regulated transcription coactivator 3 (HGNC Symbol)

Entrez gene summary

This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

Chromosome

15

Cytoband

q26.1

Chromosome location (bp)

90529925 - 90645345

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000140577 (version 78.38)

Entrez gene

64784

UniProt

Q6UUV7 (UniProt - Evidence at protein level)

neXtProt

NX_Q6UUV7

Antibodypedia

CRTC3 antibodies
 

PROTEIN VIEW

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CRTC3-001
 
CRTC3-002
 
CRTC3-012
 
CRTC3-014
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CRTC3-001 ENSP00000268184
ENST00000268184
Q6UUV7
Show all »
Show » Show » 619 67 No 0
CRTC3-002 ENSP00000416573
ENST00000420329
Q6UUV7
Show all »
Show » Show » 618 66.8 No 0
CRTC3-012 ENSP00000452640
ENST00000560098
H0YK33
Show all »
Show » Show » 91 10.2 No 0
CRTC3-014 ENSP00000452676
ENST00000558005
Show » 190 20.4 No 0