HDC

GENE INFORMATION

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Gene name

HDC

Synonyms

Description

Histidine decarboxylase (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010]

Chromosome

15

Cytoband

q21.2

Chromosome location (bp)

50241947 - 50266026

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000140287 (version 78.38)

Entrez gene

3067

UniProt

P19113 (UniProt - Evidence at protein level)

neXtProt

NX_P19113

Antibodypedia

HDC antibodies
 

PROTEIN VIEW

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HDC-001
 
HDC-004
 
HDC-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HDC-001 ENSP00000267845
ENST00000267845
P19113
Show all »
Show » Show » 662 74.1 No 0
HDC-004 ENSP00000440252
ENST00000543581
P19113
Show all »
Show » Show » 629 70.1 No 0
HDC-007 ENSP00000453183
ENST00000559683
H0YLF0
Show all »
Show » Show » 179 20 No 0