LRPPRC

GENE INFORMATION

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Gene name

LRPPRC (HGNC Symbol)

Synonyms

GP130, LRP130, LSFC

Description

Leucine-rich pentatricopeptide repeat containing (HGNC Symbol)

Entrez gene summary

This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome. [provided by RefSeq, Mar 2012]

Chromosome

2

Cytoband

p21

Chromosome location (bp)

43886508 - 43996005

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000138095 (version 78.38)

Entrez gene

10128

UniProt

P42704 (UniProt - Evidence at protein level)

neXtProt

NX_P42704

Antibodypedia

LRPPRC antibodies
 

PROTEIN VIEW

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LRPPRC-001
 
LRPPRC-002
 
LRPPRC-003
 
LRPPRC-005
 
LRPPRC-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LRPPRC-001 ENSP00000260665
ENST00000260665
P42704
Show all »
Show » Show » 1394 157.9 No 0
LRPPRC-002 ENSP00000386234
ENST00000409946
P42704
Show all »
Show » Show » 531 59.3 No 0
LRPPRC-003 ENSP00000403637
ENST00000447246
C9JCA9
Show all »
Show » Show » 359 40.1 No 0
LRPPRC-005 ENSP00000386562
ENST00000409659
B8ZZ38
Show all »
Show » Show » 504 56.3 No 0
LRPPRC-009 ENSP00000414207
ENST00000419884
H7C3W8
Show all »
Show » 77 8.7 No 0