THBS1

GENE INFORMATION

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Gene name

THBS1 (HGNC Symbol)

Synonyms

THBS, THBS-1, TSP, TSP-1, TSP1

Description

Thrombospondin 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008]

Chromosome

15

Cytoband

q14

Chromosome location (bp)

39581079 - 39599466

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000137801 (version 78.38)

Entrez gene

7057

UniProt

P07996 (UniProt - Evidence at protein level)

neXtProt

NX_P07996

Antibodypedia

THBS1 antibodies
 

PROTEIN VIEW

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THBS1-001
 
THBS1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

THBS1-001 ENSP00000260356
ENST00000260356
P07996
Show all »
Show » Show » 1170 129.4 Yes 0
THBS1-002 ENSP00000380720
ENST00000397591
A8MZG1
Show all »
Show » Show » 94 10.1 Yes 0