FGFBP1

GENE INFORMATION

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Gene name

FGFBP1 (HGNC Symbol)

Synonyms

FGFBP, HBP17

Description

Fibroblast growth factor binding protein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]

Chromosome

4

Cytoband

p15.32

Chromosome location (bp)

15935569 - 15938740

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000137440 (version 78.38)

Entrez gene

9982

UniProt

Q14512 (UniProt - Evidence at protein level)

neXtProt

NX_Q14512

Antibodypedia

FGFBP1 antibodies
 

PROTEIN VIEW

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FGFBP1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FGFBP1-001 ENSP00000371770
ENST00000382333
Q14512
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