LCP1

GENE INFORMATION

? »

Gene name

LCP1 (HGNC Symbol)

Synonyms

CP64, L-PLASTIN, LC64P, PLS2

Description

Lymphocyte cytosolic protein 1 (L-plastin) (HGNC Symbol)

Entrez gene summary

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq, Jul 2008]

Chromosome

13

Cytoband

q14.13

Chromosome location (bp)

46125920 - 46211871

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000136167 (version 78.38)

Entrez gene

3936

UniProt

P13796 (UniProt - Evidence at protein level)

neXtProt

NX_P13796

Antibodypedia

LCP1 antibodies
 

PROTEIN VIEW

? »
 
 
 
LCP1-001
 
LCP1-005
 
LCP1-006
 
LCP1-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LCP1-001 ENSP00000408052
ENST00000416500
Q5TBN3
Show all »
Show » Show » 246 27.3 No 0
LCP1-005 ENSP00000402157
ENST00000442275
Q5TBN5
Show all »
Show » Show » 66 7.4 No 0
LCP1-006 ENSP00000381581
ENST00000398576
P13796
Show all »
Show » Show » 627 70.3 No 0
LCP1-201 ENSP00000315757
ENST00000323076
P13796
Show all »
Show » Show » 627 70.3 No 0