ARHGEF4

GENE INFORMATION

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Gene name

ARHGEF4 (HGNC Symbol)

Synonyms

ASEF, KIAA1112, STM6

Description

Rho guanine nucleotide exchange factor (GEF) 4 (HGNC Symbol)

Entrez gene summary

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by this gene may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jun 2013]

Chromosome

2

Cytoband

q21.1

Chromosome location (bp)

130836916 - 131047263

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000136002 (version 78.38)

Entrez gene

50649

UniProt

Q9NR80 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NR80

Antibodypedia

ARHGEF4 antibodies
 

PROTEIN VIEW

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ARHGEF4-001
 
ARHGEF4-002
 
ARHGEF4-003
 
ARHGEF4-004
 
ARHGEF4-005
 
ARHGEF4-009
 
ARHGEF4-012
 
ARHGEF4-201
 
ARHGEF4-202
 
ARHGEF4-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARHGEF4-001 ENSP00000316845
ENST00000326016
Q9NR80
Show all »
Show » Show » 690 79.1 No 0
ARHGEF4-002 ENSP00000432267
ENST00000525839
Q9NR80
Show all »
Show » Show » 670 76.4 No 0
ARHGEF4-003 ENSP00000386794
ENST00000409359
E7EV07
Show all »
Show » 1014 108.2 No 0
ARHGEF4-004 ENSP00000389661
ENST00000438985
H0Y451
Show all »
Show » 372 40.9 No 0
ARHGEF4-005 ENSP00000387285
ENST00000409303
E9PEM0
Show all »
Show » Show » 630 71.8 No 0
ARHGEF4-009 ENSP00000348017
ENST00000355771
Q9NR80
Show all »
Show » Show » 619 71.1 No 0
ARHGEF4-012 ENSP00000432301
ENST00000532720
Show » Show » 287 33.2 No 0
ARHGEF4-201 ENSP00000376680
ENST00000392953
Q9NR80
Show all »
Show » Show » 720 81.8 Yes 0
ARHGEF4-202 ENSP00000398455
ENST00000428230
A4QPB6
Show all »
Show » 192 21.8 No 0
ARHGEF4-203 ENSP00000483548
ENST00000611048
E9PEM0
Show all »
Show » Show » 630 71.8 No 0