EPHA7

GENE INFORMATION

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Gene name

EPHA7 (HGNC Symbol)

Synonyms

Hek11

Description

EPH receptor A7 (HGNC Symbol)

Entrez gene summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Chromosome

6

Cytoband

q16.1

Chromosome location (bp)

93240020 - 93419547

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000135333 (version 78.38)

Entrez gene

2045

UniProt

Q15375 (UniProt - Evidence at protein level)

neXtProt

NX_Q15375

Antibodypedia

EPHA7 antibodies
 

PROTEIN VIEW

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EPHA7-001
 
EPHA7-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EPHA7-001 ENSP00000358309
ENST00000369303
Q15375
Show all »
Show » Show » 998 112.1 Yes 1
EPHA7-002 ENSP00000358303
ENST00000369297
Q15375
Show all »
Show » Show » 279 31.8 Yes 0