CABLES1

GENE INFORMATION

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Gene name

CABLES1 (HGNC Symbol)

Synonyms

FLJ35924, HsT2563

Description

Cdk5 and Abl enzyme substrate 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Chromosome

18

Cytoband

q11.2

Chromosome location (bp)

23134564 - 23260467

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000134508 (version 78.38)

Entrez gene

91768

UniProt

Q8TDN4 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TDN4

Antibodypedia

CABLES1 antibodies
 

PROTEIN VIEW

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CABLES1-001
 
CABLES1-002
 
CABLES1-003
 
CABLES1-004
 
CABLES1-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CABLES1-001 ENSP00000256925
ENST00000256925
Q8TDN4
Show all »
Show » Show » 633 67.6 Yes 0
CABLES1-002 ENSP00000413851
ENST00000420687
Q8TDN4
Show all »
Show » Show » 368 41.9 No 0
CABLES1-003 ENSP00000383321
ENST00000400473
Q8TDN4
Show all »
Show » Show » 306 34.6 No 0
CABLES1-004 ENSP00000461994
ENST00000580153
Show » 9 1.1 No 0
CABLES1-008 ENSP00000476575
ENST00000582882
Show » 163 18 No 0