HRH4

GENE INFORMATION

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Gene name

HRH4 (HGNC Symbol)

Synonyms

AXOR35, GPCR105, GPRv53, H4R, HH4R

Description

Histamine receptor H4 (HGNC Symbol)

Entrez gene summary

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

Chromosome

18

Cytoband

q11.2

Chromosome location (bp)

24460629 - 24479957

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000134489 (version 78.38)

Entrez gene

59340

UniProt

Q9H3N8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H3N8

Antibodypedia

HRH4 antibodies
 

PROTEIN VIEW

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HRH4-001
 
HRH4-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HRH4-001 ENSP00000256906
ENST00000256906
Q9H3N8
Show all »
Show » Show » 390 44.5 No 7
HRH4-002 ENSP00000402526
ENST00000426880
Q9H3N8
Show all »
Show » Show » 302 34.5 No 5