MYCN

GENE INFORMATION

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Gene name

MYCN (HGNC Symbol)

Synonyms

bHLHe37, MYCNOT, N-myc, NMYC

Description

V-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (HGNC Symbol)

Entrez gene summary

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

Chromosome

2

Cytoband

p24.3

Chromosome location (bp)

15940564 - 15947007

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000134323 (version 78.38)

Entrez gene

4613

UniProt

P04198 (UniProt - Evidence at protein level)

neXtProt

NX_P04198

Antibodypedia

MYCN antibodies
 

PROTEIN VIEW

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MYCN-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MYCN-001 ENSP00000281043
ENST00000281043
P04198
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