ANGPTL3

GENE INFORMATION

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Gene name

ANGPTL3 (HGNC Symbol)

Synonyms

ANGPT5

Description

Angiopoietin-like 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metablism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Feb 2013]

Chromosome

1

Cytoband

p31.3

Chromosome location (bp)

62597487 - 62606159

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000132855 (version 78.38)

Entrez gene

27329

UniProt

Q9Y5C1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y5C1

Antibodypedia

ANGPTL3 antibodies
 

PROTEIN VIEW

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ANGPTL3-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ANGPTL3-001 ENSP00000360170
ENST00000371129
Q9Y5C1
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