PCNA

GENE INFORMATION

? »

Gene name

PCNA

Synonyms

Description

Proliferating cell nuclear antigen (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

p12.3

Chromosome location (bp)

5114953 - 5126626

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000132646 (version 78.38)

Entrez gene

5111

UniProt

P12004 (UniProt - Evidence at protein level)

neXtProt

NX_P12004

Antibodypedia

PCNA antibodies
 

PROTEIN VIEW

? »
 
 
 
PCNA-001
 
PCNA-002
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PCNA-001 ENSP00000368438
ENST00000379143
P12004
Show all »
Show » Show » 261 28.8 No 0
PCNA-002 ENSP00000368458
ENST00000379160
P12004
Show all »
Show » Show » 261 28.8 No 0