H3F3B

GENE INFORMATION

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Gene name

H3F3B (HGNC Symbol)

Synonyms

H3.3B

Description

H3 histone, family 3B (H3.3B) (HGNC Symbol)

Entrez gene summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded by this gene is a member of the histone H3 family. Pseudogenes of this gene have been identified on the X chromosome, and on chromosomes 5, 13 and 17. [provided by RefSeq, Jan 2015]

Chromosome

17

Cytoband

q25.1

Chromosome location (bp)

75776434 - 75785893

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000132475 (version 78.38)

Entrez gene

3021

UniProt

P84243 (UniProt - Evidence at protein level)

neXtProt

NX_P84243

Antibodypedia

H3F3B antibodies
 

PROTEIN VIEW

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H3F3B-001
 
H3F3B-003
 
H3F3B-005
 
H3F3B-006
 
H3F3B-007
 
H3F3B-009
 
H3F3B-010
 
H3F3B-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

H3F3B-001 ENSP00000254810
ENST00000254810
P84243
Show all »
Show » Show » 136 15.3 No 0
H3F3B-003 ENSP00000466020
ENST00000586607
P84243
Show all »
Show » Show » 136 15.3 No 0
H3F3B-005 ENSP00000465813
ENST00000589599
P84243
Show all »
Show » Show » 136 15.3 No 0
H3F3B-006 ENSP00000465403
ENST00000586270
K7EK07
Show all »
Show » Show » 132 14.9 No 0
H3F3B-007 ENSP00000468714
ENST00000587560
P84243
Show all »
Show » Show » 136 15.3 No 0
H3F3B-009 ENSP00000468484
ENST00000587171
K7ES00
Show all »
Show » Show » 151 16.6 No 0
H3F3B-010 ENSP00000467165
ENST00000592643
K7EP01
Show all »
Show » Show » 113 12.8 No 0
H3F3B-011 ENSP00000466663
ENST00000591890
K7EMV3
Show all »
Show » Show » 92 10.3 No 0