CKMT2

GENE INFORMATION

? »

Gene name

CKMT2 (HGNC Symbol)

Synonyms

SMTCK

Description

Creatine kinase, mitochondrial 2 (sarcomeric) (HGNC Symbol)

Entrez gene summary

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q14.1

Chromosome location (bp)

81233285 - 81266397

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000131730 (version 78.38)

Entrez gene

1160

UniProt

P17540 (UniProt - Evidence at protein level)

neXtProt

NX_P17540

Antibodypedia

CKMT2 antibodies
 

PROTEIN VIEW

? »
 
 
 
CKMT2-001
 
CKMT2-003
 
CKMT2-004
 
CKMT2-007
 
CKMT2-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CKMT2-001 ENSP00000254035
ENST00000254035
P17540
Show all »
Show » Show » 419 47.5 No 0
CKMT2-003 ENSP00000404203
ENST00000424301
P17540
Show all »
Show » Show » 419 47.5 No 0
CKMT2-004 ENSP00000423264
ENST00000511719
D6R998
Show all »
Show » Show » 170 19 No 0
CKMT2-007 ENSP00000427635
ENST00000505060
D6RHV3
Show all »
Show » Show » 158 17.7 No 0
CKMT2-201 ENSP00000410289
ENST00000437669
P17540
Show all »
Show » Show » 419 47.5 No 0