COX4I1

GENE INFORMATION

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Gene name

COX4I1 (HGNC Symbol)

Synonyms

COX4, COX4-1

Description

Cytochrome c oxidase subunit IV isoform 1 (HGNC Symbol)

Entrez gene summary

Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. [provided by RefSeq, Jul 2008]

Chromosome

16

Cytoband

q24.1

Chromosome location (bp)

85798633 - 85807044

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000131143 (version 78.38)

Entrez gene

1327

UniProt

P13073 (UniProt - Evidence at protein level)

neXtProt

NX_P13073

Antibodypedia

COX4I1 antibodies
 

PROTEIN VIEW

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COX4I1-001
 
COX4I1-004
 
COX4I1-006
 
COX4I1-009
 
COX4I1-011
 
COX4I1-013
 
COX4I1-016
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

COX4I1-001 ENSP00000253452
ENST00000253452
P13073
Show all »
Show » Show » 169 19.6 No 1
COX4I1-004 ENSP00000454714
ENST00000564903
H3BN72
Show all »
Show » Show » 126 14.4 No 1
COX4I1-006 ENSP00000454869
ENST00000565078
H3BNI5
Show all »
Show » 43 4.8 No 0
COX4I1-009 ENSP00000457015
ENST00000561569
P13073
Show all »
Show » Show » 169 19.6 No 1
COX4I1-011 ENSP00000455030
ENST00000568794
H3BNV9
Show all »
Show » Show » 139 15.7 No 1
COX4I1-013 ENSP00000455301
ENST00000566405
H3BPG0
Show all »
Show » Show » 108 12.6 No 1
COX4I1-016 ENSP00000457513
ENST00000562336
P13073
Show all »
Show » Show » 169 19.6 No 1