HSD17B3

GENE INFORMATION

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Gene name

HSD17B3 (HGNC Symbol)

Synonyms

SDR12C2

Description

Hydroxysteroid (17-beta) dehydrogenase 3 (HGNC Symbol)

Entrez gene summary

This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq, Jul 2008]

Chromosome

9

Cytoband

q22.32

Chromosome location (bp)

96235306 - 96302152

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000130948 (version 78.38)

Entrez gene

3293

UniProt

P37058 (UniProt - Evidence at protein level)

neXtProt

NX_P37058

Antibodypedia

HSD17B3 antibodies
 

PROTEIN VIEW

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HSD17B3-005
 
HSD17B3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HSD17B3-005 ENSP00000364412
ENST00000375263
P37058
Show all »
Show » Show » 310 34.5 No 1
HSD17B3-201 ENSP00000364411
ENST00000375262
P37058
Show all »
Show » Show » 260 29.1 No 0