TRPM4

GENE INFORMATION

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Gene name

TRPM4 (HGNC Symbol)

Synonyms

FLJ20041

Description

Transient receptor potential cation channel, subfamily M, member 4 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a calcium-activated nonselective ion channel that mediates transport of monovalent cations across membranes, thereby depolarizing the membrane. The activity of the encoded protein increases with increasing intracellular calcium concentration, but this channel does not transport calcium. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]

Chromosome

19

Cytoband

q13.33

Chromosome location (bp)

49157741 - 49211836

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000130529 (version 78.38)

Entrez gene

54795

UniProt

Q8TD43 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TD43

Antibodypedia

TRPM4 antibodies
 

PROTEIN VIEW

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TRPM4-001
 
TRPM4-002
 
TRPM4-006
 
TRPM4-009
 
TRPM4-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TRPM4-001 ENSP00000252826
ENST00000252826
Q8TD43
Show all »
Show » Show » 1214 134.3 No 6
TRPM4-002 ENSP00000483753
ENST00000599628
Show » 31 3.6 No 0
TRPM4-006 ENSP00000407492
ENST00000427978
Q8TD43
Show all »
Show » Show » 1069 118.6 No 5
TRPM4-009 ENSP00000473231
ENST00000598691
M0R3H6
Show all »
Show » Show » 156 17.1 No 0
TRPM4-013 ENSP00000471236
ENST00000597316
Show » 51 5.8 No 0