FLNC

GENE INFORMATION

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Gene name

FLNC (HGNC Symbol)

Synonyms

ABP-280, ABPL, FLN2

Description

Filamin C, gamma (HGNC Symbol)

Entrez gene summary

This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

q32.1

Chromosome location (bp)

128830377 - 128859274

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000128591 (version 78.38)

Entrez gene

2318

UniProt

Q14315 (UniProt - Evidence at protein level)

neXtProt

NX_Q14315

Antibodypedia

FLNC antibodies
 

PROTEIN VIEW

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FLNC-001
 
FLNC-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FLNC-001 ENSP00000327145
ENST00000325888
Q14315
Show all »
Show » Show » 2725 291 No 0
FLNC-002 ENSP00000344002
ENST00000346177
Q14315
Show all »
Show » Show » 2692 287.3 No 0