PODXL

CANCER ATLAS

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Gene description

Podocalyxin-like

Protein class

Plasma proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Endometrial cancer

STAINING SUMMARY

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HPA002110
 
HPA045507
 
CAB016169
 
 
CAB062558
 
CAB068219
 
CAB068220
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

Strong cytoplasmic and luminal membranous positivity was observed in fraction of cells in endometrial and testicular cancers. A few gliomas and pancreatic cancers exhibited moderate to strong cytoplasmic immunoreactivity. Adenocarcinoma of head & neck cancer and a few ovarian cancers showed strong luminal membranous staining. Remaining cancer tissues were mainly negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected