EMC4

GENERAL INFORMATION

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Gene name

EMC4

Gene description

ER membrane protein complex subunit 4

Protein class

Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

7
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Strong cytoplasmic positivity was observed in Purkinje cells, neuronal cells, ganglion cells in intestinal tract and a subset of cells in adrenal gland. Fraction of cells in pancreatic islets, seminal vesicle, a subset of renal tubules and peripheral nerves showed moderate staining. Remaining normal tissues were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA053440
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Cerebellum

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

EMC4 (HGNC Symbol)

Synonyms

FLJ90746, MGC24415, PIG17, TMEM85

Description

ER membrane protein complex subunit 4 (HGNC Symbol)

Entrez gene summary

Chromosome

15

Cytoband

q14

Chromosome location (bp)

34224999 - 34230156

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000128463 (version 78.38)

Entrez gene

51234

UniProt

Q5J8M3 (UniProt - Evidence at protein level)

neXtProt

NX_Q5J8M3

Antibodypedia

EMC4 antibodies


PROTEIN BROWSER

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ENST00000249209
 
ENST00000267750
 
ENST00000557879
 
ENST00000559078
 
ENST00000559421
 
ENST00000560947
 
ENST00000561372
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EMC4-001 ENSP00000267750
ENST00000267750
Q5J8M3
Show all »
Show » Show » 183 20.1 No 2
EMC4-003 ENSP00000249209
ENST00000249209
Q5J8M3
Show all »
Show » Show » 149 16.7 No 1
EMC4-008 ENSP00000453287
ENST00000561372
H0YLP8
Show all »
Show » 125 13.9 No 1
EMC4-011 ENSP00000473881
ENST00000557879
S4R329
Show all »
Show » 72 7.8 No 0
EMC4-012 ENSP00000452672
ENST00000559421
H0YK61
Show all »
Show » 78 8.3 No 0
EMC4-013 ENSP00000454052
ENST00000559078
H0YNK8
Show all »
Show » 102 11.2 No 0
EMC4-014 ENSP00000452849
ENST00000560947
Show » 98 10.7 No 0