EMR2

GENE INFORMATION

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Gene name

EMR2 (HGNC Symbol)

Synonyms

CD312

Description

Egf-like module containing, mucin-like, hormone receptor-like 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

Chromosome

19

Cytoband

p13.12

Chromosome location (bp)

14732393 - 14778541

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000127507 (version 78.38)

Entrez gene

30817

UniProt

Q9UHX3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UHX3

Antibodypedia

EMR2 antibodies
 

PROTEIN VIEW

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EMR2-001
 
EMR2-002
 
EMR2-003
 
EMR2-007
 
EMR2-008
 
EMR2-009
 
EMR2-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EMR2-001 ENSP00000472280
ENST00000596991
Q9UHX3
Show all »
Show » Show » 812 89.5 Yes 7
EMR2-002 ENSP00000376692
ENST00000392965
Q9UHX3
Show all »
Show » Show » 765 84.1 Yes 7
EMR2-003 ENSP00000319883
ENST00000315576
Q9UHX3
Show all »
Show » Show » 823 90.5 Yes 7
EMR2-007 ENSP00000470725
ENST00000594294
Q9UHX3
Show all »
Show » Show » 774 85.2 Yes 7
EMR2-008 ENSP00000472735
ENST00000594076
Q9UHX3
Show all »
Show » Show » 730 80.3 Yes 7
EMR2-009 ENSP00000469277
ENST00000595839
Q9UHX3
Show all »
Show » Show » 681 74.9 Yes 7
EMR2-010 ENSP00000471297
ENST00000601345
M0R0K5
Show all »
Show » Show » 831 91.3 Yes 7