EDN2

GENE INFORMATION

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Gene name

EDN2 (HGNC Symbol)

Synonyms

ET2

Description

Endothelin 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

Chromosome

1

Cytoband

p34.2

Chromosome location (bp)

41478775 - 41484673

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000127129 (version 78.38)

Entrez gene

1907

UniProt

P20800 (UniProt - Evidence at protein level)

neXtProt

NX_P20800

Antibodypedia

EDN2 antibodies
 

PROTEIN VIEW

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EDN2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EDN2-001 ENSP00000361668
ENST00000372587
P20800
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