CTAG2

GENE INFORMATION

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Gene name

CTAG2 (HGNC Symbol)

Synonyms

CAMEL, CT6.2a, CT6.2b, ESO2, LAGE-1, LAGE-1a, LAGE-1b, LAGE1, MGC138724, MGC3803

Description

Cancer/testis antigen 2 (HGNC Symbol)

Entrez gene summary

This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Chromosome

X

Cytoband

q28

Chromosome location (bp)

154651972 - 154653579

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000126890 (version 78.38)

Entrez gene

30848

UniProt

O75638 (UniProt - Evidence at protein level)

neXtProt

NX_O75638

Antibodypedia

CTAG2 antibodies
 

PROTEIN VIEW

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CTAG2-001
 
CTAG2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CTAG2-001 ENSP00000247306
ENST00000247306
O75638
Show all »
Show » Show » 210 21.1 No 0
CTAG2-002 ENSP00000358598
ENST00000369585
O75638
Show all »
Show » Show » 180 18.3 No 0