COX6B1

GENE INFORMATION

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Gene name

COX6B1 (HGNC Symbol)

Synonyms

COX6B, COXG

Description

Cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) (HGNC Symbol)

Entrez gene summary

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively. [provided by RefSeq, Jan 2010]

Chromosome

19

Cytoband

q13.12

Chromosome location (bp)

35648223 - 35658861

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000126267 (version 78.38)

Entrez gene

1340

UniProt

P14854 (UniProt - Evidence at protein level)

neXtProt

NX_P14854

Antibodypedia

COX6B1 antibodies
 

PROTEIN VIEW

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COX6B1-002
 
COX6B1-003
 
COX6B1-004
 
COX6B1-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

COX6B1-002 ENSP00000376037
ENST00000392201
P14854
Show all »
Show » Show » 86 10.2 No 0
COX6B1-003 ENSP00000246554
ENST00000246554
P14854
Show all »
Show » Show » 86 10.2 No 0
COX6B1-004 ENSP00000466818
ENST00000592141
P14854
Show all »
Show » Show » 86 10.2 No 0
COX6B1-005 ENSP00000467776
ENST00000590618
Show » Show » 40 4.7 No 0