AMOT

GENE INFORMATION

? »

Gene name

AMOT (HGNC Symbol)

Synonyms

KIAA1071

Description

Angiomotin (HGNC Symbol)

Entrez gene summary

This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

q23

Chromosome location (bp)

112774503 - 112840815

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000126016 (version 78.38)

Entrez gene

154796

UniProt

Q4VCS5 (UniProt - Evidence at protein level)

neXtProt

NX_Q4VCS5

Antibodypedia

AMOT antibodies
 

PROTEIN VIEW

? »
 
 
 
AMOT-001
 
AMOT-003
 
AMOT-004
 
AMOT-005
 
AMOT-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AMOT-001 ENSP00000305557
ENST00000304758
Q4VCS5
Show all »
Show » Show » 675 72.5 No 0
AMOT-003 ENSP00000361026
ENST00000371958
A6NP16
Show all »
Show » 597 68.4 No 0
AMOT-004 ENSP00000361030
ENST00000371962
E7ERM3
Show all »
Show » 852 92.5 No 0
AMOT-005 ENSP00000429013
ENST00000524145
Q4VCS5
Show all »
Show » Show » 1084 118.1 No 0
AMOT-201 ENSP00000361027
ENST00000371959
Q4VCS5
Show all »
Show » Show » 1084 118.1 No 0