TBC1D20

GENE INFORMATION

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Gene name

TBC1D20 (HGNC Symbol)

Synonyms

C20orf140, dJ852M4.2

Description

TBC1 domain family, member 20 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that belongs to a family of GTPase activator proteins of Rab-like small GTPases. The encoded protein and its cognate GTPase, Rab1, bind the nonstructural protein 5A (NS5A) of the hepatitis C virus (HCV) to mediate viral replication. Depletion of this protein inhibits replication of the virus and HCV infection. Mutations in this gene are associated with Warburg micro syndrome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

Chromosome

20

Cytoband

p13

Chromosome location (bp)

435480 - 462553

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125875 (version 78.38)

Entrez gene

128637

UniProt

Q96BZ9 (UniProt - Evidence at protein level)

neXtProt

NX_Q96BZ9

Antibodypedia

TBC1D20 antibodies
 

PROTEIN VIEW

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TBC1D20-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TBC1D20-004 ENSP00000346139
ENST00000354200
Q96BZ9
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