SDCBP2

GENE INFORMATION

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Gene name

SDCBP2 (HGNC Symbol)

Synonyms

SITAC18, ST-2

Description

Syndecan binding protein (syntenin) 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The encoded protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Read-through transcription also exists between this gene and the upstream FKBP1A (FK506 binding protein 1A, 12kDa) gene, as represented in GeneID:100528031. [provided by RefSeq, Sep 2011]

Chromosome

20

Cytoband

p13

Chromosome location (bp)

1309909 - 1329239

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125775 (version 78.38)

Entrez gene

27111

UniProt

Q9H190 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9H190

Antibodypedia

SDCBP2 antibodies
 

PROTEIN VIEW

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SDCBP2-001
 
SDCBP2-002
 
SDCBP2-003
 
SDCBP2-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SDCBP2-001 ENSP00000371233
ENST00000381812
Q9H190
Show all »
Show » Show » 292 31.6 No 0
SDCBP2-002 ENSP00000371229
ENST00000381808
Q9H190
Show all »
Show » Show » 207 22.7 No 0
SDCBP2-003 ENSP00000354013
ENST00000360779
Q9H190
Show all »
Show » Show » 292 31.6 No 0
SDCBP2-004 ENSP00000342935
ENST00000339987
Q9H190
Show all »
Show » Show » 292 31.6 No 0