GRIA3

GENE INFORMATION

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Gene name

GRIA3 (HGNC Symbol)

Synonyms

GluA3, GLUR3, GLURC, MRX94

Description

Glutamate receptor, ionotropic, AMPA 3 (HGNC Symbol)

Entrez gene summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

q25

Chromosome location (bp)

123184153 - 123490915

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125675 (version 78.38)

Entrez gene

2892

UniProt

P42263 (UniProt - Evidence at protein level)

neXtProt

NX_P42263

Antibodypedia

GRIA3 antibodies
 

PROTEIN VIEW

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GRIA3-001
 
GRIA3-002
 
GRIA3-006
 
GRIA3-007
 
GRIA3-201
 
GRIA3-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GRIA3-001 ENSP00000478489
ENST00000620443
P42263
Show all »
Show » Show » 894 101.2 Yes 3
GRIA3-002 ENSP00000446440
ENST00000541091
P42263
Show all »
Show » Show » 894 101.2 Yes 3
GRIA3-006 ENSP00000478758
ENST00000611689
Q5XKG2
Show all »
Show » 144 16.1 Yes 0
GRIA3-007 ENSP00000479607
ENST00000616590
Q5XKG2
Show all »
Show » 144 16.1 Yes 0
GRIA3-201 ENSP00000481875
ENST00000620581
Q9UHA9
Show all »
Show » Show » 824 93.4 Yes 2
GRIA3-202 ENSP00000481554
ENST00000622768
P42263
Show all »
Show » Show » 894 101.2 Yes 3