POLR1B

GENE INFORMATION

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Gene name

POLR1B (HGNC Symbol)

Synonyms

FLJ10816, FLJ21921, RPA2, Rpo1-2

Description

Polymerase (RNA) I polypeptide B, 128kDa (HGNC Symbol)

Entrez gene summary

Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).[supplied by OMIM, Mar 2008]

Chromosome

2

Cytoband

q14.1

Chromosome location (bp)

112541915 - 112577150

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125630 (version 78.38)

Entrez gene

84172

UniProt

Q9H9Y6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H9Y6

Antibodypedia

POLR1B antibodies
 

PROTEIN VIEW

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POLR1B-001
 
POLR1B-003
 
POLR1B-005
 
POLR1B-006
 
POLR1B-007
 
POLR1B-015
 
POLR1B-201
 
POLR1B-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

POLR1B-001 ENSP00000263331
ENST00000263331
Q9H9Y6
Show all »
Show » Show » 1135 128.2 No 0
POLR1B-003 ENSP00000387143
ENST00000409894
Q9H9Y6
Show all »
Show » Show » 952 107.9 No 0
POLR1B-005 ENSP00000405358
ENST00000417433
Q9H9Y6
Show all »
Show » Show » 1079 122 No 0
POLR1B-006 ENSP00000415754
ENST00000430769
C9JJG2
Show all »
Show » Show » 114 12.7 No 0
POLR1B-007 ENSP00000388577
ENST00000438748
C9JS83
Show all »
Show » Show » 128 14.1 No 0
POLR1B-015 ENSP00000394408
ENST00000458012
H7C0D9
Show all »
Show » Show » 308 34.4 No 0
POLR1B-201 ENSP00000437914
ENST00000537335
Q9H9Y6
Show all »
Show » Show » 924 104.5 No 0
POLR1B-202 ENSP00000444136
ENST00000541869
Q9H9Y6
Show all »
Show » Show » 1173 132.2 No 0