SOX4

GENE INFORMATION

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Gene name

SOX4

Synonyms

Description

SRY (sex determining region Y)-box 4 (HGNC Symbol)

Entrez gene summary

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

p22.3

Chromosome location (bp)

21592769 - 21598619

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000124766 (version 78.38)

Entrez gene

6659

UniProt

Q06945 (UniProt - Evidence at protein level)

neXtProt

NX_Q06945

Antibodypedia

SOX4 antibodies
 

PROTEIN VIEW

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SOX4-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SOX4-001 ENSP00000244745
ENST00000244745
Q06945
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