MOCS1

GENE INFORMATION

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Gene name

MOCS1 (HGNC Symbol)

Synonyms

MOCOD

Description

Molybdenum cofactor synthesis 1 (HGNC Symbol)

Entrez gene summary

Molybdenum cofactor biosynthesis is a conserved pathway leading to the biological activation of molybdenum. The protein encoded by this gene is involved in this pathway. This gene was originally thought to produce a bicistronic mRNA with the potential to produce two proteins (MOCS1A and MOCS1B) from adjacent open reading frames. However, only the first open reading frame (MOCS1A) has been found to encode a protein from the putative bicistronic mRNA, whereas additional splice variants, whose full-length natures have yet to be determined, are likely to produce a fusion between the two open reading frames. This gene is defective in patients with molybdenum cofactor deficiency, type A. A related pseudogene has been identified on chromosome 16. [provided by RefSeq, Jan 2010]

Chromosome

6

Cytoband

p21.2

Chromosome location (bp)

39899578 - 39934551

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000124615 (version 78.38)

Entrez gene

4337

UniProt

Q9NZB8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NZB8

Antibodypedia

MOCS1 antibodies
 

PROTEIN VIEW

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MOCS1-001
 
MOCS1-002
 
MOCS1-005
 
MOCS1-006
 
MOCS1-008
 
MOCS1-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MOCS1-001 ENSP00000362282
ENST00000373186
Q9NZB8
Show all »
Show » Show » 385 43.1 No 0
MOCS1-002 ENSP00000362291
ENST00000373195
Q9NZB8
Show all »
Show » Show » 533 58.5 No 0
MOCS1-005 ENSP00000344794
ENST00000340692
Q9NZB8
Show all »
Show » Show » 636 70.1 No 0
MOCS1-006 ENSP00000416478
ENST00000425303
Q9NZB8
Show all »
Show » Show » 636 70.2 No 0
MOCS1-008 ENSP00000362284
ENST00000373188
Q9NZB8
Show all »
Show » Show » 385 43.1 No 0
MOCS1-010 ENSP00000410809
ENST00000432280
Q9NZB8
Show all »
Show » Show » 356 40.4 No 0