HIF3A

GENE INFORMATION

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Gene name

HIF3A (HGNC Symbol)

Synonyms

bHLHe17, IPAS, MOP7, PASD7

Description

Hypoxia inducible factor 3, alpha subunit (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]

Chromosome

19

Cytoband

q13.32

Chromosome location (bp)

46297046 - 46343433

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000124440 (version 78.38)

Entrez gene

64344

UniProt

Q9Y2N7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y2N7

Antibodypedia

HIF3A antibodies
 

PROTEIN VIEW

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HIF3A-003
 
HIF3A-004
 
HIF3A-006
 
HIF3A-007
 
HIF3A-012
 
HIF3A-023
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HIF3A-003 ENSP00000366898
ENST00000377670
Q9Y2N7
Show all »
Show » Show » 669 72.4 No 0
HIF3A-004 ENSP00000434653
ENST00000472815
H0YDZ5
Show all »
Show » Show » 450 48.6 No 0
HIF3A-006 ENSP00000300862
ENST00000300862
Q9Y2N7
Show all »
Show » Show » 667 72.4 No 0
HIF3A-007 ENSP00000244303
ENST00000244303
Q9Y2N7
Show all »
Show » Show » 600 64.4 No 0
HIF3A-012 ENSP00000435200
ENST00000533145
E9PLC8
Show all »
Show » Show » 148 16 No 0
HIF3A-023 ENSP00000471560
ENST00000600383
M0R104
Show all »
Show » Show » 594 64.1 No 0