SEMG2

GENERAL INFORMATION

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Gene name

SEMG2

Gene description

Semenogelin II

Protein class

Plasma proteins
Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (kidney)
GTEx:Tissue enriched (prostate)

Protein evidence

Evidence at protein level

Protein localization

Selective cytoplasmic expression in seminal vesicle.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA042767 , HPA042835
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Seminal vesicle



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (kidney)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (prostate)

Organ

Expression



GENE INFORMATION

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Gene name

SEMG2 (HGNC Symbol)

Synonyms

SGII

Description

Semenogelin II (HGNC Symbol)

Entrez gene summary

The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

q13.12

Chromosome location (bp)

45221300 - 45224458

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000124157 (version 78.38)

Entrez gene

6407

UniProt

Q02383 (UniProt - Evidence at protein level)

neXtProt

NX_Q02383

Antibodypedia

SEMG2 antibodies


PROTEIN BROWSER

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ENST00000372769
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SEMG2-001 ENSP00000361855
ENST00000372769
Q02383
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