SDC4

GENERAL INFORMATION

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Gene name

SDC4

Gene description

Syndecan 4

Protein class

Cancer-related genes
Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression, most abundant in glandular cells of the gastrointestinal tract, gall bladder and cells in the placenta.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA005716 , CAB013240
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

SDC4 (HGNC Symbol)

Synonyms

amphiglycan, ryudocan, SYND4

Description

Syndecan 4 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

q13.12

Chromosome location (bp)

45325288 - 45348424

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000124145 (version 78.38)

Entrez gene

6385

UniProt

P31431 (UniProt - Evidence at protein level)

neXtProt

NX_P31431

Antibodypedia

SDC4 antibodies


PROTEIN BROWSER

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ENST00000372733
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SDC4-001 ENSP00000361818
ENST00000372733
P31431
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Show » Show » 198 21.6 Yes 1