C4BPA

GENE INFORMATION

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Gene name

C4BPA (HGNC Symbol)

Synonyms

C4BP

Description

Complement component 4 binding protein, alpha (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q32.2

Chromosome location (bp)

207104262 - 207144972

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000123838 (version 78.38)

Entrez gene

722

UniProt

P04003 (UniProt - Evidence at protein level)

neXtProt

NX_P04003

Antibodypedia

C4BPA antibodies
 

PROTEIN VIEW

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C4BPA-001
 
C4BPA-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

C4BPA-001 ENSP00000356037
ENST00000367070
P04003
Show all »
Show » Show » 597 67 Yes 0
C4BPA-002 ENSP00000403386
ENST00000421786
A6PVY5
Show all »
Show » 152 16.9 Yes 0