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GENE INFORMATION
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The gene information section lists the gene name (HUGO Gene Nomenclature Committee ( HGNC) name if available), any approved gene synonyms, Ensembl gene description, and the Entrez gene summary from the National Center for Biotechnology Information.
The chromosomal and cytoband location of the gene according to Ensembl is reported together with the Ensembl gene identifier and Ensembl database version.
The Entrez gene identifier for the gene is also given. If any of the protein products of
the gene is linked to a UniProt KB/SWISS-PROT entry, links to the UniProt and the
neXtProt databases for these proteins are displayed.
There is also a link to the Antibodypedia portal where validation data for antibodies produced by other suppliers
against this gene can be found.
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PROTEIN VIEW
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The protein view displays protein features. The tabs at the top of the protein view section can be used to switch between the different splice variants encoded by this gene. The mouse over function displays additional data for the features in the protein view.
At the top of the protein view, the maximum percent sequence identity of the protein to all other proteins from other human genes is shown, using a sliding window of 10 aa residues
(HsID 10) or 50 aa residues (HsID 50) ( read more).
If a signal peptide is predicted by a majority of the signal peptide predictors SPOCTOPUS,
SignalP 4.0, and
Phobius
(turquoise) and/or transmembrane regions (orange) are predicted by MDM, these are displayed.
Low complexity regions are shown in yellow and InterPro regions in green.
Common (purple) and unique (grey) regions between different splice variants of the gene are also displayed
( read more), and at the bottom of the protein view is the protein scale.
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PROTEIN INFORMATION
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The protein information section displays the alternative protein-coding transcripts (splice variants) encoded by this gene, according to the Ensembl database.
The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant.
The data in the UniProt column can be expanded to show links to all matching
UniProt identifiers for this protein.
The protein classes to which this protein has been assigned are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.
The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column.
The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors
SPOCTOPUS,
SignalP 4.0, and
Phobius) and the number of predicted transmembrane region(s) (according to
MDM) are also reported.
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Splice variant |
Ensembl |
UniProt |
Protein class |
Gene ontology |
Length (aa) |
Molecular mass (kDa) |
Signal peptide (predicted) |
Transmembrane regions (predicted)
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NFE2-001 |
ENSP00000397185
ENST00000435572
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Q16621 Show all »
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Q16621 [Direct mapping]Transcription factor NF-E2 45 kDa subunit A8K3E0 [Target identity:100%; Query identity:100%]Nuclear factor (Erythroid-derived 2), 45kDa, isoform CRA_a {ECO:0000313|EMBL:EAW96771.1}; cDNA FLJ78141, highly similar to nuclear factor erythroid 2 isoform f=basic leucine zipper protein {ECO:0000313|EMBL:BAF83253.1}; cDNA FLJ78153, highly similar to nuclear factor erythroid 2 isoform f=basic leucine zipper protein {ECO:0000313|EMBL:BAF83244.1}; cDNA, FLJ93708, Homo sapiens nuclear factor (erythroid-derived 2), 45kDa (NFE2),mRNA {ECO:0000313|EMBL:BAG36023.1} F8W1N9 [Target identity:91%; Query identity:100%]Transcription factor NF-E2 45 kDa subunit {ECO:0000313|Ensembl:ENSP00000446929}
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Predicted intracellular proteins Transcription factors Basic domains Protein evidence (Kim et al 2014)
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373 |
41.5 |
No |
0 |
NFE2-002 |
ENSP00000447558
ENST00000553070
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Q16621 Show all »
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Q16621 [Direct mapping]Transcription factor NF-E2 45 kDa subunit A8K3E0 [Target identity:100%; Query identity:100%]Nuclear factor (Erythroid-derived 2), 45kDa, isoform CRA_a {ECO:0000313|EMBL:EAW96771.1}; cDNA FLJ78141, highly similar to nuclear factor erythroid 2 isoform f=basic leucine zipper protein {ECO:0000313|EMBL:BAF83253.1}; cDNA FLJ78153, highly similar to nuclear factor erythroid 2 isoform f=basic leucine zipper protein {ECO:0000313|EMBL:BAF83244.1}; cDNA, FLJ93708, Homo sapiens nuclear factor (erythroid-derived 2), 45kDa (NFE2),mRNA {ECO:0000313|EMBL:BAG36023.1} F8W1N9 [Target identity:91%; Query identity:100%]Transcription factor NF-E2 45 kDa subunit {ECO:0000313|Ensembl:ENSP00000446929}
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Predicted intracellular proteins Transcription factors Basic domains Protein evidence (Kim et al 2014)
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373 |
41.5 |
No |
0 |
NFE2-003 |
ENSP00000312436
ENST00000312156
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Q16621 Show all »
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Q16621 [Direct mapping]Transcription factor NF-E2 45 kDa subunit A8K3E0 [Target identity:100%; Query identity:100%]Nuclear factor (Erythroid-derived 2), 45kDa, isoform CRA_a {ECO:0000313|EMBL:EAW96771.1}; cDNA FLJ78141, highly similar to nuclear factor erythroid 2 isoform f=basic leucine zipper protein {ECO:0000313|EMBL:BAF83253.1}; cDNA FLJ78153, highly similar to nuclear factor erythroid 2 isoform f=basic leucine zipper protein {ECO:0000313|EMBL:BAF83244.1}; cDNA, FLJ93708, Homo sapiens nuclear factor (erythroid-derived 2), 45kDa (NFE2),mRNA {ECO:0000313|EMBL:BAG36023.1} F8W1N9 [Target identity:91%; Query identity:100%]Transcription factor NF-E2 45 kDa subunit {ECO:0000313|Ensembl:ENSP00000446929}
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Predicted intracellular proteins Transcription factors Basic domains Protein evidence (Kim et al 2014)
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373 |
41.5 |
No |
0 |
NFE2-004 |
ENSP00000439120
ENST00000540264
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Q16621 Show all »
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Q16621 [Direct mapping]Transcription factor NF-E2 45 kDa subunit A8K3E0 [Target identity:100%; Query identity:100%]Nuclear factor (Erythroid-derived 2), 45kDa, isoform CRA_a {ECO:0000313|EMBL:EAW96771.1}; cDNA FLJ78141, highly similar to nuclear factor erythroid 2 isoform f=basic leucine zipper protein {ECO:0000313|EMBL:BAF83253.1}; cDNA FLJ78153, highly similar to nuclear factor erythroid 2 isoform f=basic leucine zipper protein {ECO:0000313|EMBL:BAF83244.1}; cDNA, FLJ93708, Homo sapiens nuclear factor (erythroid-derived 2), 45kDa (NFE2),mRNA {ECO:0000313|EMBL:BAG36023.1} F8W1N9 [Target identity:91%; Query identity:100%]Transcription factor NF-E2 45 kDa subunit {ECO:0000313|Ensembl:ENSP00000446929}
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Predicted intracellular proteins Transcription factors Basic domains Protein evidence (Kim et al 2014)
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373 |
41.5 |
No |
0 |
NFE2-005 |
ENSP00000446929
ENST00000553198
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F8W1N9 Show all »
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F8W1N9 [Target identity:100%; Query identity:100%]Transcription factor NF-E2 45 kDa subunit {ECO:0000313|Ensembl:ENSP00000446929}
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Predicted intracellular proteins Protein evidence (Kim et al 2014)
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343 |
38.2 |
No |
0 |
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