SRGN

GENE INFORMATION

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Gene name

SRGN (HGNC Symbol)

Synonyms

PPG, PRG, PRG1

Description

Serglycin (HGNC Symbol)

Entrez gene summary

This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. [provided by RefSeq, Jul 2010]

Chromosome

10

Cytoband

q22.1

Chromosome location (bp)

69088106 - 69104811

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000122862 (version 78.38)

Entrez gene

5552

UniProt

P10124 (UniProt - Evidence at protein level)

neXtProt

NX_P10124

Antibodypedia

SRGN antibodies
 

PROTEIN VIEW

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SRGN-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SRGN-001 ENSP00000242465
ENST00000242465
P10124
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