CD80

GENE INFORMATION

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Gene name

CD80 (HGNC Symbol)

Synonyms

B7-1, B7.1, CD28LG, CD28LG1

Description

CD80 molecule (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011]

Chromosome

3

Cytoband

q13.33

Chromosome location (bp)

119524293 - 119559602

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000121594 (version 78.38)

Entrez gene

941

UniProt

P33681 (UniProt - Evidence at protein level)

neXtProt

NX_P33681

Antibodypedia

CD80 antibodies
 

PROTEIN VIEW

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CD80-001
 
CD80-002
 
CD80-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD80-001 ENSP00000264246
ENST00000264246
P33681
Show all »
Show » Show » 288 33 Yes 1
CD80-002 ENSP00000418364
ENST00000478182
P33681
Show all »
Show » Show » 288 33 Yes 1
CD80-201 ENSP00000373165
ENST00000383669
P33681
Show all »
Show » Show » 256 29.4 Yes 0