B4GALT4

GENE INFORMATION

? »

Gene name

B4GALT4 (HGNC Symbol)

Synonyms

beta4Gal-T4

Description

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 (HGNC Symbol)

Entrez gene summary

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

q13.32

Chromosome location (bp)

119211732 - 119241103

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000121578 (version 78.38)

Entrez gene

8702

UniProt

O60513 (UniProt - Evidence at protein level)

neXtProt

NX_O60513

Antibodypedia

B4GALT4 antibodies
 

PROTEIN VIEW

? »
 
 
 « 
 
B4GALT4-001
 
B4GALT4-002
 
B4GALT4-003
 
B4GALT4-005
 
B4GALT4-007
 
B4GALT4-010
 
B4GALT4-011
 
B4GALT4-012
 
B4GALT4-015
 
B4GALT4-016
 
B4GALT4-017
 
B4GALT4-019
 
B4GALT4-020
 
 » 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

B4GALT4-001 ENSP00000420161
ENST00000483209
O60513
Show all »
Show » Show » 344 40 Yes 0
B4GALT4-002 ENSP00000352144
ENST00000359213
O60513
Show all »
Show » Show » 344 40 Yes 0
B4GALT4-003 ENSP00000417226
ENST00000467604
C9J3R8
Show all »
Show » Show » 301 35 Yes 0
B4GALT4-005 ENSP00000377360
ENST00000393765
O60513
Show all »
Show » Show » 344 40 Yes 0
B4GALT4-007 ENSP00000419275
ENST00000459778
Show » 6 0.7 No 0
B4GALT4-010 ENSP00000420535
ENST00000470111
C9JE00
Show all »
Show » Show » 55 6.3 Yes 0
B4GALT4-011 ENSP00000417958
ENST00000479150
C9J5S0
Show all »
Show » Show » 118 13.4 Yes 0
B4GALT4-012 ENSP00000418436
ENST00000493932
C9J644
Show all »
Show » Show » 42 4.8 Yes 0
B4GALT4-015 ENSP00000419916
ENST00000473887
C9JY38
Show all »
Show » 21 2.5 No 0
B4GALT4-016 ENSP00000419919
ENST00000491906
C9JY35
Show all »
Show » Show » 25 3.2 No 0
B4GALT4-017 ENSP00000417188
ENST00000475803
C9J4S5
Show all »
Show » Show » 136 15.5 Yes 0
B4GALT4-019 ENSP00000418278
ENST00000459820
Show » 2 0.2 No 0
B4GALT4-020 ENSP00000417527
ENST00000471675
C9JA31
Show all »
Show » Show » 62 7 No 0