TRIM25

GENE INFORMATION

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Gene name

TRIM25 (HGNC Symbol)

Synonyms

EFP, RNF147, ZNF147

Description

Tripartite motif containing 25 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q22

Chromosome location (bp)

56887909 - 56914038

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000121060 (version 78.38)

Entrez gene

7706

UniProt

Q14258 (UniProt - Evidence at protein level)

neXtProt

NX_Q14258

Antibodypedia

TRIM25 antibodies
 

PROTEIN VIEW

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TRIM25-001
 
TRIM25-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TRIM25-001 ENSP00000323889
ENST00000316881
Q14258
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Show » Show » 630 71 No 0
TRIM25-201 ENSP00000445961
ENST00000537230
Q14258
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Show » Show » 630 71 No 0