EPX

GENE INFORMATION

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Gene name

EPX (HGNC Symbol)

Synonyms

EPO, EPP, EPX-PEN

Description

Eosinophil peroxidase (HGNC Symbol)

Entrez gene summary

This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded precursor protein is processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a cluster of three peroxidase genes at chromosome 17q23. Mutations in this gene result in eosinophil peroxidase deficiency. [provided by RefSeq, Sep 2009]

Chromosome

17

Cytoband

q22

Chromosome location (bp)

58192737 - 58205174

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000121053 (version 78.38)

Entrez gene

8288

UniProt

P11678 (UniProt - Evidence at protein level)

neXtProt

NX_P11678

Antibodypedia

EPX antibodies
 

PROTEIN VIEW

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EPX-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EPX-001 ENSP00000225371
ENST00000225371
P11678
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