NFYB

GENE INFORMATION

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Gene name

NFYB (HGNC Symbol)

Synonyms

CBF-A, HAP3, NF-YB

Description

Nuclear transcription factor Y, beta (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q23.3

Chromosome location (bp)

104117077 - 104138289

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000120837 (version 78.38)

Entrez gene

4801

UniProt

P25208 (UniProt - Evidence at protein level)

neXtProt

NX_P25208

Antibodypedia

NFYB antibodies
 

PROTEIN VIEW

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NFYB-001
 
NFYB-003
 
NFYB-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NFYB-001 ENSP00000240055
ENST00000240055
P25208
Show all »
Show » Show » 207 22.8 No 0
NFYB-003 ENSP00000447486
ENST00000551727
P25208
Show all »
Show » Show » 207 22.8 No 0
NFYB-004 ENSP00000448250
ENST00000551446
F8VSL3
Show all »
Show » Show » 131 14.5 No 0