TMPO

GENERAL INFORMATION

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Gene name

TMPO

Gene description

Thymopoietin

Protein class

Disease related genes
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Nuclear membranous expression in most tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA008150 , CAB009847
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

TMPO (HGNC Symbol)

Synonyms

LAP2, LEMD4, TP

Description

Thymopoietin (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in this gene are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, May 2010]

Chromosome

12

Cytoband

q23.1

Chromosome location (bp)

98515512 - 98550379

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000120802 (version 78.38)

Entrez gene

7112

UniProt

P42166 (UniProt - Evidence at protein level), P42167 (UniProt - Evidence at protein level)

neXtProt

NX_P42166, NX_P42167

Antibodypedia

TMPO antibodies


PROTEIN BROWSER

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ENST00000261210
 
ENST00000266732
 
ENST00000343315
 
ENST00000393053
 
ENST00000556029
 
ENST00000556678
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TMPO-001 ENSP00000266732
ENST00000266732
P42166
Show all »
Show » Show » 694 75.5 No 0
TMPO-002 ENSP00000450627
ENST00000556029
P42167
Show all »
Show » Show » 454 50.7 No 1
TMPO-005 ENSP00000376773
ENST00000393053
P42167
Show all »
Show » Show » 345 38.7 No 1
TMPO-006 ENSP00000261210
ENST00000261210
P42167
Show all »
Show » Show » 248 27.4 No 0
TMPO-014 ENSP00000340251
ENST00000343315
G5E972
Show all »
Show » Show » 414 46.3 No 1
TMPO-015 ENSP00000451552
ENST00000556678
H0YJH7
Show all »
Show » 237 26.9 No 0